News & Events
The Carolinas Medical Center will bring together scientists and clinicians working in the field of the dystroglycanopathies for its “Fourth International Workshop for Glycosylation Defects in Muscular Dystrophies”, on April 16/17, 2015. For more information on the workshop please go to: http://www.carolinashealthcare.org/md-international-workshop
SATURDAY August 15th, 2015 – Iowa City The Iowa Wellstone Center presents The Dystroglycanopathies: 2015 Patient and Family Conference Featuring talks from physicians and researchers, Q&A, laboratory tours, networking, and social gathering. Appointments for study exams available Friday August 14th and Sunday August 16th. Event information and registration forms will be available soon! Questions? Contact Continue Reading »
We are excited to announce the release of a new diagnostic program for the LGMDs! We have joined together with several other LGMD family foundations to create a new website lgmd-diagnosis.org where undiagnosed individuals with a muscle problem can take a quiz to see if they qualify for free genetic sequencing, sponsored by our consortium Continue Reading »
The “LGMD2I Patient Network” is an online portal where patients will be able to track their health and environment information in real-time, as a community. After realizing the willingness of patients to share details on their health and environment through the LGMD2I Facebook group, but also recognizing the limitations of this group regarding its capacity Continue Reading »
New Online Tool Accelerates Diagnosis of Muscular Dystrophies SEATTLE—The Jain Foundation and LGMD2I Research Fund announce the release of ALDA (Automated LGMD Diagnostic Assistant), their updated and expanded Limb-Girdle Muscular Dystrophy (LGMD) subtyping tool. LGMDs are genetic diseases that cause progressive muscle weakness, sometimes involving the heart and central nervous system. The more Continue Reading »
SATURDAY JULY 20, 2013 – Iowa City The Iowa Wellstone Center presents The Dystroglycanopathies: 2013 Patient and Family Conference Featuring talks from physicians and researchers, Q&A, laboratory tours, networking, and social gathering Appointments for study exams available Friday July 19 and Sunday July 21 Event information and registration forms will be available soon! Questions? Contact Continue Reading »
The LGMD2I Research Fund, the Samantha Brazzo Foundation and Cure CMD will jointly fund a research project to support drug screening on mutant forms of FKRP, in the search for compounds that restore normal protein function. The project, led by Dr. Sebahattin Cirak at the Children’s National Medical Center, will use a novel approach for Continue Reading »
The LGMD2I Research Fund has recently awarded a grant to support a stem cell therapy project using genetically-corrected LGMD2I patient cells. In this project, induced pluripotent stem cells (iPS cells) from LGMD2I patients will first be corrected for their genetic defect using novel recombinant DNA techniques. Corrected cells will be then induced to become muscle Continue Reading »
The Carolinas Medical Center brought together scientists and clinicians working in the field of the dystroglycanopathies for its “Third International Workshop for Glycosylation Defects in Muscular Dystrophies”, on April 18/19, 2013. For more information on the workshop please go to: http://www.carolinashealthcare.org/md-international-workshop
The second edition of the “Dystroglycanopathies: Patient and Family Conference” took place on August 18th in Iowa City. The conference focused on the basics of the dystroglycanopathies, research updates, and provided opportunities to network with clinicians, researchers and other patients and families. It was a lot of fun! For those who couldn’t make it Continue Reading »
The first newsletter of the International FKRP registry has just been published. It contains up-to-date information on the registry, patient organisations and the newest research efforts. You can download the newsletter, which all registered patients have received by e-mail, as PDF file here.
Dr. Claudia Mitchell, Program Director of the LGMD2I Research Fund, presented a poster on the importance of sub-typing Limb Girdle Muscular Dystrophies at the MDA Clinical Conference that took place in Las Vegas from March 4th to 6th. Click here to view poster.
The Samantha Brazzo Foundation, the LGMD2I Research Fund and Cure CMD will jointly fund a research project to support the development and characterization of a stable FKRP zebrafish model to be used for screening of potential drug candidates. Candidate drugs will also be tested in another zebrafish model of dystroglycanopathy (Pomt2 deficiency) in parallel to Continue Reading »
Myomatrix 2012 is a scientific conference dedicated to exploring the junction between muscle and extracellular matrix, the myomatrix, a central point in the pathogenesis of LGMD2I and other alpha-dystroglycan-related dystrophies. The conference will take place in Reno, Nevada, from April 22nd to 24th, 2012. For more details and registration information, please go to: http://curecmd.org/myomatrix.
The LGMD2I Research Fund has recently awarded 4 new research grants. These grants will help us further understand the disease and potentially open new therapeutic avenues. Check our Awarded Grants page for more detail on each grant.
Welcome to the LGMD2I Research Fund website! We are a non-profit private foundation focused on finding treatments for Limb Girdle Muscular Dystrophy 2I and other alpha-dystroglycan-related dystrophies. We fulfill our mission by promoting basic research with specific focus on LGMD2I, by fostering clinical trial readiness and by supporting translation of promising scientific discoveries into Continue Reading »